Thursday, January 17, 2008

Collin is recovering from HSP (Henoch Sohonlein Purpura)

The doctors either have a hard time communicating to me or I am just not understanding the words that come out of their mouth. They say he has Hives one day the next it's HSP and so on. So, today he has HSP. I have copied below a web page about HSP. Thankfully, Collin seems on the road to recovery. He still has the rash but the joint pain has subsided, which was horrible. His kidneys don't seem to be affected. Really, it's a waiting game. I am not sure, why are all the problems with Collin and Cameron so strange. They don't see too many of these cases and are completely odd.

What is HSP?Henoch-Schonlein purpura (HSP or anaphylactoid purpura) is a form of blood vessel inflammation or vasculitis. There are many different conditions that feature vasculitis. Each of the forms of vasculitis tends to involve certain characteristic blood vessels. HSP affects the small arterial vessels called capillaries in the skin and frequently the kidneys. HSP results in skin rash (most prominent over the buttocks and behind the lower extremities associated with joint inflammation (arthritis) and sometimes cramping pain in the abdomen.
What causes HSP?HSP occurs most often in the spring and frequently follows an infection of the throat or breathing passages. HSP seems to represent an unusual reaction of the body's immune system that is in response to this infection (either bacteria or virus). Aside from infection, drugs can also trigger the condition. HSP occurs most commonly in children, but persons of all age groups can be affected.
What are symptoms of HSP?Classically, HSP causes skin rash, pain in the abdomen, and joint inflammation (arthritis). Not all features need be present for the diagnosis. The rash of skin lesions appears in gravity-dependent areas, such as the legs. The joints most frequently affected with pain and swelling are the ankles and the knees. Patients with HSP can develop fever. Inflammation of the blood vessels in the kidneys can cause blood and/or protein in the urine. Serious kidney complications are infrequent, but can occur. Sometimes a biopsy of skin and/or kidney is used in assisting the diagnosis, which is typically made based on the clinical findings.
Symptoms usually last approximately a month. Recurrences are not frequent, but do occur.
What is the treatment for HSP?While HSP is generally a mild illness that resolves spontaneously, it can cause serious problems in the kidneys and bowels. The rash can be very prominent, especially on the lower extremities.
The treatment of HSP is directed toward the most significant area of involvement. Joint pain can be relieved by antiinflammatory medications, such as aspirin or
ibuprofen (Motrin). Some patients can require cortisone medications, such as prednisone, especially those with significant abdominal pain or kidney disease. With more severe kidney disease, cyclophosphamide (Cytoxan) has been used to suppress the immune system. Infection, if present, can require antibiotics.
What are the consequences of HSP?The prognosis for patients with HSP is generally excellent. Nearly all patients have no long-term problems. The kidney is the most serious organ involved when it is affected. Rarely, patients can have serious long-term kidney damage or an abnormal bowel folding called intussusception. A few patients have recurrences of symptoms for a couple of years after the onset of the illness.
Recent data shows that HSP in adults is generally more severe than in children. Adults have more severe kidney involvement and can require more aggressive treatment. The ultimate outcome, however, is usually very good for both adults and children.